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RF Diffusion and Protein Design

On this episode, Oskar, Sanjana, and Hayden interview David Juergens and Joe Watson from David Baker’s lab about their recent publication “Broadly applicable and accurate protein design by integrating structure prediction networks and diffusion generative models.” Using the same principles underlying the image-generating software DALL-E, the Baker lab has been able to create software that will generate functional proteins for tasks ranging from therapeutics to materials science.